Biological Screening of a Large Combinatorial Library
نویسندگان
چکیده
منابع مشابه
Direct screening of a dynamic combinatorial library using mass spectrometry.
A dynamic combinatorial library (DCL) screening approach is described that permits direct identification of the effective (from ineffective) combination of building blocks in the equilibrating DCL. The approach uses Fourier transform ion cyclotron resonance mass spectrometry (FTICR MS) together with sustained off-resonance irradiation collision activated dissociation (SORI-CAD) to detect noncov...
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ژورنال
عنوان ژورنال: Journal of Biomolecular Screening
سال: 1996
ISSN: 1087-0571,1552-454X
DOI: 10.1177/108705719600100111